David Friedberg on AI-First Startups & the Future of Biology, Business & Creativity | AI Basics

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In this episode, Jason chats with David Friedberg—CEO of Ohalo Genetics and co-host of the All-In Podcast—about how AI is transforming agriculture and startups. David introduces Ohalo’s “Boosted Breeding” technology, which enables plants to inherit 100% of genes from both parents, potentially doubling crop yields. They also discuss building AI-first companies, genome language models, and the future of creativity in an AI-driven world.

Timestamps:
(0:00) David Friedberg joins Jason to discuss AI Basics.
(1:44) How AI leveled up hiring and operations at startups
(5:46) AI and economic opportunities, complex problem-solving, and leadership’s role
(11:48) How to build an AI-first company culture
(16:48) AI’s transformative impact on biology and DNA sequencing
(21:36) The “GLM” – GPT for DNA Is already in production
(23:17) Biology meets AI: designing perfect plants with CRISPR and genome models
(32:08) Is the “Age of Abundance” around the corner?
(35:56) Democratization of creativity through AI: personalized Star Wars musicals & the future of media

Uncover more valuable insights from AI leaders in Google Cloud’s ‘Future of AI: Perspectives for Startups’ report. Discover what 23 AI industry leaders think about the future of AI—and how it impacts your business. Read their perspectives here: https://goo.gle/futureofai

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Listen here:
Apple: https://podcasts.apple.com/us/podcast/this-week-in-startups-audio/id315114957
Spotify: https://open.spotify.com/show/6ULQ0ewYf5zmsDgBchlkr9
Overcast: https://overcast.fm/itunes315114957/this-week-in-startups-audio

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Date: May 22, 2025

25 thoughts on “David Friedberg on AI-First Startups & the Future of Biology, Business & Creativity | AI Basics

  1. What if you edit crops to all grow to X height and you interrupt the hierarchy of the food heights of the undergrowth. That means animals that feed on the small plants underneath the canopy and in the long run you interrupt this animals growth cycle of the animal or ecosystem.

    But it’s like said this has been happening for years and now it is just fine tuned.

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